ea0073s21.1 | Symposium 21: Hot topics in neuroendocrine tumours | ECE2021
Lines Kate
Epigenetic mechanisms are gaining increasing interest in oncology, both as drivers of tumourigenesis and as potential novel therapeutic targets. This is particularly relevant in neuroendocrine neoplasms (NENs), as a key tumour suppressor gene involved in NEN development, multiple endocrine neoplasia type 1 (MEN1), plays a critical role in epigenetic regulation of gene expression through micro RNA (miRNA) and histone modification pathways. MEN1 mutations can g...