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Endocrine Abstracts (2021) 73 EP9 | DOI: 10.1530/endoabs.73.EP9

1The Military Hospital of Tunis, Urology, Tunis, Tunisia; 2The Military Hospital of Tunis, Endocrinology, Tunis, Tunisia


Background

Paraganglioma of the urinary bladder is rarely encountered. Its clinical signs and symptoms are usually nonspecific.

Case presentation

We report a case of a 48-year-old woman who presented with recurrent hematuria for last 2 months with a recently detected hypertension. Computed tomography (CT) revealed a lobulated mass arising from the posterior wall of the urinary bladder and protruding into the vesical lumen measuring 3 cm with inhomogeneous postcontrast enhancement. Transurethral resection of the mass has instantly produced a hypertensive peak (200/110 mmHg) leading to an interruption of operation. Pathology of the specimen found a pheochromocytoma. Our patient denied a history of dizziness, sweating, and palpitations during micturition. Hormonal evaluation showed a normal level of both plasmatic and urinary metanephrine and normetanephrine. Metastatic workup was negative. Both adrenal glands were normal at CT. MIBG scan showed an increased localized activity in the bladder. After preoperative stabilization of hypertension and medical preparation, a complete transurethral resection of the tumor was performed. This case was discussed at a tumor board meeting and surveillance was decided. The patient has been disease-free for 9 months.

Conclusion

In patients with unusual, striking symptoms and an increase in blood pressure with micturition, diagnosis of pheochromocytoma of the urinary bladder must be considered. Imaging will help in confirming the diagnosis and localizing the tumor. Surgical removal is the treatment of choice.

Volume 73

European Congress of Endocrinology 2021

Online
22 May 2021 - 26 May 2021

European Society of Endocrinology 

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