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Endocrine Abstracts (2021) 73 AEP685 | DOI: 10.1530/endoabs.73.AEP685

ECE2021 Audio Eposter Presentations Thyroid (157 abstracts)

Iodized salt is sufficient to obtain an adequate nutritional status of iodine in pregnant woman

Silvia González Martínez 1 , Ana Isabel Escudero Gomis 2 , Elias Delgado 2 & Edelmiro Luis Menendez Torre 2


1Hospital Vital Álvarez Buylla, Santullano, Spain; 2Hospital Universitario Central de Asturias, Oviedo, Spain


Introduction

Iodine is an essential micronutrient used by the thyroid gland to produce thyroid hormones. Iodine deficiency during pregnancy is related to impaired neurocognitive development of fetus and neonate. The WHO recommends iodization of salt as main measure to prevent iodine deficiency disorders. In pregnant population other international organizations recommend the use of iodine supplements to guarantee adequate nutritional status of iodine (median urinary iodine concentration [UIC] ≥ 150 µg/l). The objectives of the study are to know nutritional status of iodine in our pregnant women and its relationship with iodine intake.

Materials and methods

Descriptive and analytical observational study carried out in 2017 in 318 women in the first trimester of pregnancy at Hospital Universitario Central de Asturias, Spain. Pregnant women with diagnosis of thyroid disease before pregnancy or multiple gestations were excluded. Information on dietary habits was collected by midwives in the primary care centers. The questionnarie contained items related to consumption of iodized salt, dairy products and iodine supplements. UIC was determinated in a first morning urine sample. The statistical analysis was performed using the R program (R Development Core Team), version 3.6.0, applying the Chi-square and Student’s T statistical tests.

Results

Mean age of pregnant women was 34.10 ± 5.45 years, with a mean gestation age of 7.19 ± 2 weeks.

Results of the iodine intake questionnaire were as follows

– Consumption of iodized salt: 51.10%

– Consumption of dairy products (≥ 2 servings day): 48.9%

– Use of iodine supplement: 87.08%

Median UIC (Q1–Q3) was 171.5 µg/l (116–265 µg/l). 60.4% of pregnant women had ioduria greater ≥150 µg/l.

  UIC ≥150 μg/l UIC < 150 μg/l P Median UIC
(Q1–Q3) μg/l
P
Iodized salt
No 55 (48.7%) 58 (51.33%) 0.001 147 (102–206) 0.016
Yes 97 (69.3%) 43 (30.7%) 191.5 (131.5–285)
Dairy products
<2 servings/day 78 (56.1%) 61 (43.9%) 0.269 168 (96–258) 0.48
≥ 2 servings/day 84 (62.7%) 50 (37.3%) 172 (122.25–255.75)
Iodine supplement
No 21 (53.9%) 18 (46.1%) 0.455 158.5 (113–199.5) 0.027
Yes 157 (60.1%) 104 (39.9%) 172.5 (116–285.75)

Conclusions

Our pregnant population presents an adequate nutritional status of iodine. In our sample, the intake of iodized salt was sufficient to obtain an adequate UIC, being the main measure to achieve it. The use of iodine supplements increases UIC but has no protective effect against UIC <150 µg/l. We agree with the WHO recommendation on the use of iodized salt in pregnant women.

Volume 73

European Congress of Endocrinology 2021

Online
22 May 2021 - 26 May 2021

European Society of Endocrinology 

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