Endocrine Abstracts

Pituitary apoplexy is a rare complication of a pituitary adenoma consisting in hemorrhage or infarctation usually in patients with preexisting comorbidities. SARS-COV-2 infection is a ’new’ disease known to determine vascular impairment in some patients, although studies on this particular issue are still rolling. We present the case of a 64 years old woman suffering from mild hypertension (well-controlled under sartans) who in may 2020 got the SARS-COV-2 infection and because of high fever (38, 5 C) was hospitalized and placed on treatment with azitromicyne and antinflamatory treatment. 4 days later she develops severe headache with light visual impairment. The symptoms were considered to be in the context of the viral infection so no further investigation were made, but still the patient was placed on corticosteroids with good outcome. Three monts later she presents to our endocrinology department with severe asthenia, hypotension, generalized edema and constipation. She is immediately diagnosed with panhypopytuitarism and a pituitary IRM is being made which describes a pituitary adenoma with a hemorrhage zone of approximately 2 cm. Under treatment corticosteroids and thyroid hormones the evolution is good. The neurosurgical evaluation doesn’t consider appropriate to undergo surgery at this time. 6 moths later the patient is in still in very good condition and the IRM reveals slight shrinkage of the tumor and some resorbtion of the hemorrhage area. The particularity of this case we consider to be the non-existence of comorbidities usually associated with pituitary apoplexy and also the late diagnosis of this life-threatening condition, mainly because of the low-experience with COVID manifestation and the general effect of the pandemic both on medical services and also on patients addressability during this period.