Endocrine Abstracts

Objective

To evaluate the combined pathology of the thyroid and mammary glands in normally cycling women

Materials and Methods

We have examined normally cycling 265 women aged 18 to 56 years. The modeling was performed using the SPSS 17.0 statistical software package.

Results

the combined pathology of the thyroid and mammary glands was detected in 149 women (56.2%) of the number of examined women. Isolated pathology of the thyroid gland in the age group from 18 to 35 years old was defined in 29 people (23.0%); isolated breast pathology - in 36 (28.6%); combined pathology of the thyroid and mammary glands - in 49 women (38.9%). In the group from 36 to 44 years old, isolated thyroid pathology was diagnosed in 14 women (14.9%); isolated pathology of the mammary gland - in 13 (13.8%), combined pathology of the thyroid and mammary glands - in 63 women (67%). In the group of 45 years and older, isolated pathology of the thyroid gland was diagnosed in 5 women (11.1%); isolated breast pathology - in 1 (2.2%); combined pathology of the thyroid and mammary glands - in 37 women (82.2%). The incidence of combined pathology of the thyroid and mammary glands in all age groups is higher than the isolated pathology of the thyroid gland (group 1 - χ² = 7.43; P <0.05; group 2 - χ² = 52.06; P < 0.001; group 3 - χ² = 44.72; P <0.001). The incidence of combined pathology in groups from 36 to 44 years old and 45 years and older is higher than isolated breast pathology (group 2 – χ² = 54.45; P <0.001; group 3 – χ² = 57.76; P <0.001). The incidence of concomitant pathology is significantly higher in group 3 (compared with women in group 1 - (χ² = 10.17; P = 0.001).

Conclusions

The incidence of combined pathology of the thyroid and mammary glands in all age groups is higher than the isolated pathology of the thyroid gland.