Endocrine Abstracts

Introduction

Pituitary adenomas generate 10–15% of primary brain tumors. Most of these adenomas are benign and orginate from the epithelial cells of the adenohypophysis. Pituitary adenomas can occur in all age groups, but most common in the third and sixth decades. In this study, we are investigated the demographic characteristics of pituitary adenomas and non-adenoma lesions that admission to the Bozyaka Education and Research Hospital Endocrinology and Metabolic Diseases outpatient clinic between 2018–2019.

Materials and methods

93 patient who have pituitary adenomas and non-adenoma lesions that admission to the Bozyaka Education and Research Hospital Endocrinology and Metabolic Diseases outpatient clinic between 2018–2019; detailed anamnesis, pituitary hormone results and pituitary MR images were retrospectively analyzed.

Results

The mean age of patients was 44, 7 (range 19–93). Of 93 patients, we were seen 70% were female (n:66) and 29% were male. (n:27) We were found that microadenoma 56% (n:53), macroadenoma in 31% (n:29), empty cella 2% (n:2), partial empty cella 6%(n:6), craniopharyngioma 3% (n:3), rathke cleft cyst 1% (n:1) of the patients who admitted to the study. Among the patients diagnosed with macroadenoma, the mean age of male patients was 58, 3 (n:13), and the mean age of female patients was 48.9 (n:16). The mean age of female patients who diagnosed with microadenoma was 38 (n:44), and the mean age of male patients who diagnosed with microadenoma was 46, 1. (n:9). When the patients were evaluated according to hormone secretion function; 68% (n:64) of the patients examined were prolactinoma, 6, 4% (n: 6) acromegaly, 13, 9% (n:13) were nonfunctional adenoma. Majority of the patients (%77, 9) who diagnosed with prolactinoma were female. (n: 53)

Conclusion

When both macroadenoma and microadenoma were evaluated, we found that the average age in men was higher than in women. As a result of the study, we determined microadenomas were more common in women and noticed at an younger, however; observed less frequently in men, but diagnosed in older ages. When pituitary lessions were evaluated according to hormone secretion function, prolactinoma was the most common. As a result of our study, the majority of patients followed up with the diagnosis of microadenoma with medical treatment (n:43) while the majority of patients diagnosed with macroadenoma are followed together with surgical and medical treatment.(n:16). In this study, we aimed to make demographic analysis of patients with pituitary adenoma and non adenoma lesions who applied to our hospital. The results of our study were found to be consistent with the literature.