Endocrine Abstracts

Adrenocortical Carcinoma (Adrenal Cancer or ACC) is a rare malignancy. It requires multidisciplinary care to manage the multiple endocrine and oncologic manifestations of the disease. We will use the recently published international ACC Guidelines to illustrate essential components of the standard of care work-up, diagnosis, and management of ACC. As an understanding of genetics is becoming increasingly mainstream in cancer biology and care including adrenocortical carcinoma (Adrenal Cancer or ACC), we will discuss the burgeoning work in endocrine genetics and current efforts to translate such work into better strategies for diagnosis and for the development of targeted therapies for the treatment of adrenal cancer. Additional goals of this talk are to understand the role of genetics in the pathobiology of adrenal cancer and to discuss how such knowledge is transforming how we care for our patients.