Endocrine Abstracts

The aim of investigation: To study the tomographic characteristic of the chiasmal-sellar region (CSD) in patients with volumetric formations of the hypothalamic-pituitary region.

Material and research methods: We for the period from 2018 to 2020. 34 patients with various pituitary adenomas were examined. Of these, men – 15 (44.1%), women – 19 (55.9%). Average age: men amounted to 37.12 years, women – 38, 15 years. The research methods included: 1) general clinical (study of endocrine, neurological status, anthropometry 2) instrumental (perimetry for all colors, fundus, visual acuity, ECG, densitometry, CT/MRI of the Turkish saddle, etc.), 3) hormonal blood tests (STH, IGF-1, LH, FSH, PRL, TSH, ACTH, prolactin, etc.)

Research results: Among the 34 patients examined, various formations of the Sellar region were identified: non-functional pituitary adenoma (NFPA) – 21 patients, prolactinoma – 3, Itsenko-Cushing’s disease – 4, craniopharyngoma –2, acromegaly –4. Depending on the size of the pituitary adenoma, the following pituitary changes were found on CT/MRI: microadenomas (<10 mm) – 2 patients (5.8%), mesoadenomas (11–20 mm) – 3 patients (8.8%), macroadenomas (up to 30 mm) – 4 patients (11.6%), giant – (more than 30 mm) – 25 patients (73.5%) Distribution of patients according to topographic anatomical classification of the growth side of the pituitary adenoma B. Kadashev (2007) showed that the most frequently observed pituitary adenomas with endosuprasellar growth – 13 bx (38.2%), with infracellular growth – 2 (5.8%), with laterosellar growth – 3 (8.8%), with an antesellar growth of –1 (2.9%), with a retrocellular growth – 1 (2.9%), with a total growth option – 14 bx (41.1%).

Conclusions: 1) Among the examined 34 patients with volumetric formations of the sellar region, patients with giant pituitary adenomas (more than 3 cm) predominated – 25 cases (73.5%). 2) The most common endo-suprasellar growth of the neoplasm was 13 cases (38.2%).