Endocrine Abstracts

Primary adrenal lymphoma(PAL) is very rare and constitutes <1% of cases of extranodal lymphomas. Most common subtype of PAL is diffuse large B cell lymphoma. A 46-year-old male patient without any underlying disease was admitted to our hospital with a complaint of bilateral back pain, cough and fever. His laboratory tests revealed a hemoglobin: 5 g/dl (14–17.5), white blood cell: 3.8 10³/µl (4.4–11.3), platelet: 111 10³/µl (130–403). No pathological findings were detected in bone marrow biopsy. Abdominal MRI and chest CT revealed that bilateral adrenal mass without any lymphadenopathy. PET/CT showed a mass of 73×53 mm on the left adrenal gland and a mass of 145×90 mm on the right adrenal gland. Adrenal function was evaluated as non-functional adrenal mass. Surgical right adrenalectomy was performed. Postoperative basal cortisol level: 12.25 µg/dl (6.02–18.4), adrenal insufficiency is not detected. Histopathological examinationreported as diffuse large B cell lymphoma. R-CHOP chemotherapy was planned by consulting hematology. The 5-year cancer spesific survival rate for primary adrenal lymphoma is 38% and it should be considered as the differential diagnosis of the adrenal mass, especially when they are bilateral and grow rapidly.