ECE2020 ePoster Presentations Hot topics (including COVID-19) (57 abstracts)
Primary aldosteronism: follow up of 17 cases
Wafa Benothman 1 , Ghada Saad 1 , Imen Halloul 1 , Asma Benabdelkrim 1 , Yosra Hasni 1 , Maha Kacem 1 , Molka Chaieb 1 , Amel Maaroufi 1 & Koussay Ach
Farhat Hached Hospital, Endocrinology, Sousse, Tunisia
Introduction: Primary and nonsuppressible hypersecretion of aldosterone is an increasingly recognized, but still underdiagnosed, cause of hypertension. Our objective is to determine the evolution features of primary aldosteronism (PA) patients.
Patients and Methods: Retrospective study of 17 patients with PA confirmed biochemically and histologically when operated.
Results: The mean age was 41.9 ± 9.3 years at PA diagnosis, and 6 of them (35.3%) were male. Twelve patients had adenoma producer of aldosterone (APA), 3 had bilateral adrenal hyperplasia idiopathic (HIA), 1 had familial PA and the last one had primary unilateral adrenal hyperplasia (PUAH). Patients were followed for a period between 6 months and 21 years, with an average of 4.3 years. Eleven out of twelve APA, 1 HIA and 1 PUAH had unilateral adrenalectomy using laparoscopic technique. Of postoperative complications, we noted hypertensive spikes in 5 patients and severe hypokalemia in 2 cases. Eight patients had a remission without antihypertensive drug except one case with biological ‘normo-aldosteronism’ and essential hypertension. Familial aldosteronism was treated with dexamethasone. Hypertension was controlled with 2.9 ± 1.2 antihypertensive drugs. An average reduction of 0.9 (range: –1 and 3) in the number of these drugs was obtained in post-therapy; both medical and surgical. All patients had normokalemia. Morbidity was independent of the etiology and the treatment.
Conclusion: The overall treatment goal in patients with PA is to prevent the adverse outcomes. Individualization of treatment according to the anatomo-clinic type determined an improvement of the patients’ prognosis without however a significant effect on the morbidity.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more