Endocrine Abstracts

Background: Thyroid cancer is the most common malignant disease of the endocrine system. Thyroid cancer represents above 1% of all malignancies. There is a paucity of data on thyroid cancer in Nepalese patients.

Aim: The aim of this study is to explore clinical profile of thyroid cancer patients diagnosed and managed in our center.

Methods: A total of 70 patients with thyroid cancer were included in the sample from March 2013 to December 2019. The OPD records of these patients were reviewed for their clinical profiles including age, sex, operation procedure, location of tumor, TNM staging, ATA risk category, RAI ablation and dose of RAI ablation. The collected data was analyzed by using descriptive and inferential statistical with SPSS version 20.

Result: The findings of the study revealed that 81.4% were females and 18.6% were males. The mean age was 37.3(±9) years and mean BMI was 27(±4) kg/m². Location of tumor in left lobe was 34.28%, right lobe was 52.85% and both lobes were 12.87%. Among those patients 25.71% had righthemithyroidectomy, 10% left hemithyroidectomy and 64.29% total thyroidectomy. All had papillary thyroid carcinoma. According to American Thyroid Association (ATA) Risk Stratification System, 62.85% had low risk category, 35.71% of patients intermediate risk category and 1.44% high risk category. According to TNM classification, 14.2% patients had stage T1a, 38.5% stage T1b, 32.8% stage T2, 11.5%, stage T3a, 1.5% stage T3b, 1.5% stage T4a respectively.18.5% of patients underwent RAI ablation. Doses of RAI given to patients were 100 mCi (5.7%), 121 mCi (1.42%), 150 mCi (1.42%), 64 mCi (1.42%), 65 mCi (4.28%), 80 mCi (1.42%) and 95 mCi (1.42%). Mean dose of RAI was 96.42 mCi.

Conclusion: Thyroid cancer was mostly seen in females and young age. Most patients had right lobe cancer. More than half of the patients had total thyroidectomy. Most patients had low risk category. Only 18.5% patients underwent RAI ablation.