ECE2020 ePoster Presentations Thyroid (122 abstracts)
Prevalence of incidentally finding of papillary thyroid cancer among patients with sporadic medullary thyroid cancer
Georgios Boutzios 1 , Nefeli Tomara 2 , Evgenia Kotsifa 2 , Eleni Koukoulioti 1 , Alexis Terra 2 , Stylianos Kykalos 2 , Eleftherios Spartalis 2 , Konstantinos Vagianos 2 & Gerasimos Tsourouflis 2
1National and Kapodistrian University of Athens, Pathophysiology, Athens, Greece; 2National and Kapodistrian University of Athens, Second Department of Propedeutic Surgery, Athens, Greece
Introduction: The coexistence of papillary thyroid cancer (PTC) and medullary TC (MTC) is rare. Previous retrospective studies have shown a prevalence up to 19%. The aim of our study was to assess the prevalence of PTC in patients with sporadic MTC.
Methods: This is a single-center retrospective study of an endocrinology outpatient clinic at a Tertiary, General, University Hospital. Patients who had undergone total thyroidectomy with central neck compartment and had histologically confirmed MTC were included in the study. Also, a RET oncogene analysis was performed in all patients. Patients with positive RET were excluded from the study.
Results: A total of twenty-seven patients were analyzed, of whom females were 40.7% (11/27). The mean age of patients was 58.19 ± 13.1 years. The prevalence of PTC was 33.3% (9/27). 22.2% (6/27) of the patients underwent re-operation for lymph node invasion. Distal metastases appeared in 14.8% of the patients (4/27).
Conclusion: According to our data the prevalence of PTC as incidental finding in patients with MTC is higher compared to previous studies. The cause underlying the phenomenon of MTC and papillary PTC is still unclear.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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