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Endocrine Abstracts (2020) 70 EP491 | DOI: 10.1530/endoabs.70.EP491

Complejo Hospitalario de Navarra


Objective: Incidentally discovered thyroid microcarcinomas (TMc) are tumors with a maximal diameter ≥1 cm, indetified during a detailed histopathology examination following a thyroidectomy performed for reasons not pertaining to malignancies of the thyroid gland.

Methods: We included 1555 patients who underwent a total thyroidectomy for benign disease between January 2005 and December 2018. Patients with post-surgical pathology consistent with thyroid cancer with a maximal tumor diameter ≥1 cm were excluded. The incidence of TMc was identified and compared between the different subgroups.

Results: The mean age of the 1555 patients was 53.5 ± 13.8 years and the proportion of women was higher (82.5%, n = 1283). 1206 patients (77.6%) had a preoperative diagnosis of nodular goiter. 136 cases of TMc were identified (prevalence 8.7%). The majority of cases were papillary TMc (91.2%, n = 124).

There were no differences in prevalence according to sex (women 8.6% vs. men 9.6%, P = 0.601) or age (mean age 54.4 ± 12 years in patients with TMc vs. 53.4 ± 14, P = 0.415).

The prevalence was significantly lower in patients with Graves’ disease (5.2% vs. 9.6% in nodular goiter and 9.3% in chronic lymphocytic thyroiditis, P = 0.037).

Conclusion: In our study the prevalence of TMc in patients who underwent total thyroidectomy for benign disease was 8.7%.

The prevalence was significantly lower in patients with Graves’disease.

Volume 70

22nd European Congress of Endocrinology

Online
05 Sep 2020 - 09 Sep 2020

European Society of Endocrinology 

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