ECE2020 ePoster Presentations Reproductive and Developmental Endocrinology (37 abstracts)
Quality of life questionnaires in PCOS- the impact of hirsutism
Zoran Gluvic 1 , Milena Lackovic 1 , Vladimir Samardzic 1 , Marina Vujovic 1 , Vesna Popovic-Radinovic 1 , Jelena Tica 1 , Milan Obradovic 2 , Emina Sudar-Milovanovic 2 & Esma R. Isenovic 2
1Zemun Clinical Hospital, Endocrinology and Diabetes, Zemun, Serbia; 2Institute of Nuclear Sciences Vinca, Laboratory for radiobiology and molecular genetics, Belgrade, Serbia
Introduction: Polycystic ovary syndrome is the most frequent ovarian dysfunction during the reproductive period. Its presence significantly impacts on the final scores of various Quality-of-Life (QoL) questionnaires. This pilot study aims to analyze the impact of hirsutism (H), as the component of PCOS, on the scores of determined generic (General Health Questionnaire-12, GHQ12) and disease-specific questionnaires (Polycystic Ovary Syndrome Questionnaire, PCOSQ) in PCOS subjects.
Material and Methods: A pilot cross-sectional study involved 30 age- and BMI-matched subjects recruited at the Outpatient Endocrinology Department. The examinees are divided into two groups depending on the H- distribution score, determined by Ferriman-Gallwey (FG) scale (group 1: FG ≤ 8 and group 2: FG > 9). Examinees independently fulfilled both questionnaires (GHQ12 and PCOSQ), and the responses are rank-transformed and presented as scores. Statistical analyses were performed by SPSS for Windows 18.0.
Results: Mean GHQ12, overall, and H-domain of the PCOSQ score of the study population were 12 ± 7 (2–26), 5 ± 1 (2–7), and 6 (2–7), respectively. GHQ12 and overall PCOSQ scores statistically negatively correlated as well as the H-domain of PCOSQ and FG scores. Concerning the study groups, the GHQ12 score is higher in the FG > 9 group along with PCOSQ and H domain of PCOSQ scores, which are less in FG > 9 comparing to FG ≤ 8 group.
Conclusion: Our results suggest that H associated with PCOS directly impacts on general and disease-specific aspects of QoL. Therefore, it is of particular interest to assess the patient’s attitude about H presence.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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