Endocrine Abstracts

Both pituitary and adrenal gland metastases of lung cancer are very rare. A 79-year-old male patient with diabetes mellitus and hypertension was admitted to our hospital because of a mass in the lungs of the thorax CT. TSH: <0.005 UIU/ml (0.27–4.2), free T4: 0.794 ng/dl (0.93–1.7). Other pituitary hormones were also examined: FSH: 0.708 mIU/ml (1.5–12.4), LH: <0.1 mIU/ml (1.7–8.6), prolactin: 12.7 ng/ml (4.04–15.2), total testosterone: <0.025 ng/ml (1.93–7.4), cortisol: 1 µg/dl (6.02–18.4) was found to be. Pituitary MRI showed an infiltrative mass in the hypothalamus and stalk. PET/CT showed a malignant mass in the right hilar area, metastatic lymph nodes in the mediastinum, and diffuse metastasis in the left adrenal and bones. Pathological diagnosis in trucut needle biopsy from the right supraclavicular lymph node: Reported as metastasis of non-small cell lung carcinoma. The pituitary and adrenal masses were accepted as lung cancer metastasis. The patient was started on prednisolone 5mg, levothyroxine 25 µg/day. Diabetes insipitus was not considered due to lack of increase in urine volume and normal urine density and serum sodium levels. Patient oncology and radiation oncology were consulted and radiotherapy and chemotherapy were planned. Although fatigue is a common symptom in lung cancer cases, it should be kept in mind that metastasis to the pituitary and/or adrenal gland may occur in these patients