Endocrine Abstracts

Introduction: Ceylon cinnamon (CC) has shown its interest in insulin resistance, type2 diabetes and weight loss. In this study, we aimed to evaluate the effects of CC on anthropometric indices in patients with polycystic ovary syndrome (PCOS).

Methods: We performed a prospective interventional study, including 13 patients with PCOS, diagnosed according to the Rotterdam criteria, patients having received neither diet education nor Metformin. At T0 all our patients had, a dietary survey, anthropometric measurements: weight, height, waist seize, and impedance. During the intervention, they received a 500 mg capsule of CC three times a day (designed and prepared for the study), without changing their eating habits and physical activity, diabetic patients were excluded of the study.

Results: After 8 weeks (T1), we found a reduction in the mean of the waist seize (delta = –3.4 ± 4.74 cm et P = 0.02), a significant reduction in the waist size/height Ratio (delta = –0.22 ± 0.03 et P = 0.02), a non-significant reduction in the average BMI (delta = –0.32 ± 1.34 kg/m²) and an insignificant reduction in all components of body mass with a maximum for the fat mass at the level of the trunk (delta = –1.3 ± 10.89 kg).

Conclusion: These results could be explained by the anti-obesogenic effect of CC and lead us to suggest it as an etiopathogenic treatment for PCOS.