Endocrine Abstracts

Bulgaria is also among the countries with national data on the prevalence of Diabetes published in the Diabetes Atlas of the International Diabetes Federation’2019, but did not provide data on the incidence of Hyperglycemia in pregnant Bulgarian women.

Purpose: The Bulgarian Society of Endocrinology organized and conducted screening for Hyperglycemia in pregnant women in 2019.

Material and Methods: 547 pregnant women from 10 regions of Bulgaria (84 settlements) were examined, with an average age of 30 ± 5 y, an average BMI at screening 26.15 ± 7.28 kg/m2, distributed by trimesters – I (n – 111, 20.3%), II (n – 275, 50.4%), III (n – 161, 29.3%). The diagnostic criteria for hyperglycemia in pregnant women were in compliance with FIGO’2015 / WHO’2013 and NICE’2015.

Results: Hyperglycemia was detected in 74 (13.52%) of the pregnant women according to oGTT screening data, with 5.66% (n – 31) diagnosed with early pregnancy and 7.86% (n – 43) – Gestational Diabetes Mellitus (GDM). There is no evidence of pre–pregnancy hyperglycemia or antidiabetic medication. Family burden with Diabetes was found in 210 pregnant women (38.4%). This family burden is present in 58.1% of all pregnant women with hyperglycemia (n – 43/74) – in 67.7% of pregnant women with early hyperglycemia (n – 21/31) and in 51.2% of pregnant women with GDM (n – 22/43). It appears that the risk of hyperglycemia is twice as high in the presence of familial diabetes with 20.4% (n – 43/210) compared to the lack of familial diabetes with 9.2% (n – 31/337). The average weight before pregnancy of the whole group is 63.68 ± 14.36 kg, and during pregnancy it reaches 70.60 ± 14.50 kg. The average weight before pregnancy is 71.00 ± 16.30 kg of pregnant women with established hyperglycemia during pregnancy, which plays an important role in unlocking glucose intolerance.

Conclusion: The high incdence of hyperglycemia in pregnant Bulgarian women requires changes in the health system to diagnose this disorder in a timely manner.