Endocrine Abstracts

Introduction: Type 1 diabetes can be associated with one or more other autoimmune pathologies in case of predisposing immune background.

The aim of our study was to research the autoimmune pathologies associated with type 1 diabetes and to describe the clinical and biological characteristics of this population.

Patients and Methods: This is a retrospective descriptive study including 26 patients with type 1 diabetes with at least one autoimmune pathology associated with diabetes.

Results: The average age was 35.7 ± 8.6 years. The sex ratio was 0.23. Diabetes had evolved for an average of 17.4 ± 6.8 years. The average body mass index (BMI) was 28.2 ± 3.2 kg/m². The average HbA1C was 9.1 ± 2.2%. The average creatinine clearance was 99.2 ± 12.3 ml/min (CKD–EPI). The most widely described degenerative complication was retinopathy (28.1%). Hashimoto’s thyroiditis was the autoimmune disease most associated with diabetes (73%) followed by celiac disease (19.2%). Only one cas of vitiligo and another case of Biermer’s anemia had been found. All cases of thyroiditis were diagnosed after diabetes, as was the case with Biermer’s disease. Vitiligo preceded the diagnosis of diabetes. Celiac disease preceded diabetes in the majority of cases.

Conclusion: The frequent association of autoimmune pathologies with diabetes encourages them to be screened regularly so that they are managed on time.