Endocrine Abstracts

Introduction: Bariatric surgery is an effective treatment in order to achieve an important weight loss and improvement of metabolic comorbidities. This study aimed to assess the clinical factors that can influenced on evolution of type 2 diabetes (T2D) and obesity patients after bariatric surgery.

Methods: We conducted a cohort study with a sample of patients with type 2 diabetes and class II obesity or above who underwent bariatric surgery at Hospital Universitario Puerta del Mar (Cadiz) from January 2005 to December 2016. We evaluated demographic variables, clinical and analytical parameters, anthropometric measurements and surgery complication rates. We analized the variables before and two years after surgery. The multivariate analysis includes the possible clinical factors that predict T2D remission two years after bariatric surgery.

Results: 83 patients were included with a mean age of 44.13 ± 10.38 years. Two years after surgery, the percentage of overweight lost was 63.43 ± 18.59% and T2D was resolved in 79.5%. The body mass index range (RR: 1.886; P = 0.022), T2D duration more than five years (RR: 0.022; P = 0.040), baseline insulin treatment (RR: 0.001; P = 0.009) and absence of macrovascular complications (RR: 34.667; P = 0.002) were related with T2D remission. 15.6% of patients presented early complications and 20.5% developed late complications.

Conclusions: In our setting, bariatric surgery is an effective and safe technique for sustained weight loss in the mid-term, with a high rate of T2D’s resolution. An absence of insulin treatment, higher baseline BMI, shorter T2DM duration and absence of macrovascular complications are factors predictive of diabetes remission after bariatric surgery.