Endocrine Abstracts

Introduction: Diabetes is one of the most common chronic diseases in multimorbid population and one of the most frequently detected conditions in multimorbid disease clusters. Approximately 40% of diabetic patients have three or more coexisting chronic conditions.

Aim: To assess the frequency (percentage) of chronic conditions co-occurring with diabetes in multimorbid Lithuanian population.

Methods: Database fromthe Lithuanian National Health Insurance Fund under the Ministry of Health covering the period from 2012 till 2014was used. We exploited a reduced chronic diseases list with the diagnostic codes of ICD-10-AM (I11; I20; I25; I50; I48; E11; E06.3; E89; J44; J45; M05; M15-M19; M80; M81; M54; G54; G55). A series of heat maps for co-occurrence of 17 (diabetes included) chronic conditions were developed. Heat maps were stratified by age and gender to displaythe frequencies of chronic conditions dyads. Chronic conditions were included into the heat maps if the frequency of co-occurrence with type 2 diabetes mellitus (E11) was 10% and more.

Results: Data of 103367 patients with diabetes (63.0% female) were analyzed. Hypertensive heart disease (I11) and angina pectoris (I20) were the most common chronic conditions associated with E11 for both genders in all age groups. I11 varied from 61.4% to 77.3% and from 84.5% to 91.1% with the highest frequency of 77.3% in the 60–69 years age group and 91.1% in the same age group in female and male respectively. Meanwhile I20 varied from 13.4% to 38.1% and from 21.7% to 50% with the highest frequency of 38.1% in the 70–75 years age group and 50% in the same age group in female and male respectively. Atrial fibrillation and flutter (I48) co-occurred with E11 earlier in male (50–59 years age group) than in female (70–75 years age group). Chronic obstructive pulmonary disease co-occurred with E11 only in male group and ranged 13.1% in the 70–75 years age group.9 chronic conditions were associated with E11 only in male, age groups of 50–59 and 70–75 years.

Conclusions: The most commonly associated conditions with diabetes were hypertensive heart disease and angina pectoris. There were differences in gender: chronic obstructive pulmonary disease was associated with diabetes only in male and atrial fibrillation and flutter co-occurred with diabetes earlier in male than in female. The number and frequencies of associations increased with age in both gender groups.