ECE2020 Audio ePoster Presentations Diabetes, Obesity, Metabolism and Nutrition (285 abstracts)
Hand grip strength is correlated with peripheral neuropathy and metabolic control in patients with diabetes
Aura Diana Reghina 1,2 , Ana Maria Balea 2 , Mirela Iancu 2 , Laura Ilinca 2 , Anca Diana Niculica 1 & Simona Fica 1,2
1University of Medicine and Pharmacy Carol Davila, Endocrinology and Diabetes, Bucharest, Romania; 2Elias University Hospital, Endocrinology and Diabetes, Bucharest, Romania
Background: Peripheral neuropathy is the most prevalent chronic complication in diabetes and increases the risk of sarcopenia in these patients. Hand grip strength (HGS) measurement is a good predictor for the presence of sarcopenia.
The aim of the study was toevaluate HGS in diabetes patients with and without neuropathy and the clinical and paraclinical parameters that are correlated with HGS.
Methods: We evaluated 102 diabetes patients by clinical examination, Michigan Neuropathy Screening Instrument Questionnaire (MNSI-Q) and laboratory measurements. HGS was measured by grip strength dynamometer.
Results: Mean age was 62.8 ± 8.6 years, 64% were women and mean duration of diabetes was 13.7 ± 8.1 years and 43% of patients were diagnosed with peripheral neuropathy. Patients with peripheral neuropathy had higher duration of diabetes 16.8 ± 8.4 vs 11.4 ± 7.3 years (P = 0.001) and a lower HGS 24.5 ± 9.7 kg vs 30.3± 13.8 kg (P = 0.06). Prevalence of peripheral neuropathy was similar in women and men. HGS was similar in women with or without neuropathy but HGS was significantly lower in men with neuropathy 33.3 ± 6.8 kg vs 43 ± 8.3 kg (P = 0.004). HGS was corelated with glycated hemoglobin in the whole group (r = −0.283, P = 0.03) and was negatively correlated with age (β = −0.601, P = 0.005) and MNSI-Q score (β = −0.36, P = 0.05) in men but not in women.
Conclusion: HGS is significantly correlated with the presence of peripheral neuropathy in men but not in women. HGS measurementisa very useful and easy to use tool in clinical practice to estimate the risk of sarcopenia in men with neuropathy.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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