Searchable abstracts of presentations at key conferences in endocrinology
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22nd European Congress of Endocrinology

Online
05 Sep 2020 - 09 Sep 2020

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Europe's leading endocrinology congress showcasing the very best in the study and treatment of endocrine disorders.

Plenary Lectures

Mechanisms for SARS-CoV-2 cell entry

ea0070pl4 | Mechanisms for SARS-CoV-2 cell entry | ECE2020

SARS-CoV-2 entry into cells and its inhibition

Pöhlmann Stefan

The coronavirus disease 2019 (COVID-19) has devastating consequences. The establishment of antiviral intervention targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, is urgently needed. However, such approaches require the identification of virus-host cell interactions essential for viral spread and pathogenesis. The viral spike protein (S) mediates the first step in SARS-CoV-2 infection, viral entry into target cells, a...