ea0070pl4 | Mechanisms for SARS-CoV-2 cell entry | ECE2020
Pöhlmann Stefan
The coronavirus disease 2019 (COVID-19) has devastating consequences. The establishment of antiviral intervention targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, is urgently needed. However, such approaches require the identification of virus-host cell interactions essential for viral spread and pathogenesis. The viral spike protein (S) mediates the first step in SARS-CoV-2 infection, viral entry into target cells, a...