Endocrine Abstracts

Communication between microbiota and the host is critical to sustaining the vital functions of the healthy host, and disruptions of this homeostatic coexistence are associated with a range of diseases including obesity and T2D. Microbiota-derived metabolites act both as nutrients and as messenger molecules to shape host pathophysiology. Succinate, which has the distinction of being produced by both the host and microbiota, is quickly becoming a poster child for these metabolit...