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Endocrine Abstracts (2020) 70 AEP886 | DOI: 10.1530/endoabs.70.AEP886

1Zemun Clinical Hospital, Endocrinology, Belgrade, Serbia; 2Institute of Nuclear Sciences Vinca, Belgrade, Serbia


Introduction: Ectopic thyroid tissue is a rare developmental abnormality with the prevalence of 1 per 100.000–300.000 persons in the general population. It is most commonly detected in younger women and presented as lingual thyroid. Here we report a rare case of ectopic thyroid tissue in the left adrenal gland.

Case report: A 29-year old female without previous medical history was incidentally diagnosed with left adrenal gland mass detected on routine abdominal ultrasound check-up. There were no clinical findings suggestive to cortisol or androgen excess. Native abdominal CT scan revealed hyperdense (40 HU) left adrenal gland mass 4.8 × 2.5 cm in diameter, with 7% of relative washout enhancement observed in contrast scans. Abdominal MRI showed T2W phase isodense lesion demonstrating signal loss in T1W phase. Thyroid ultrasonography didn’t show any thyroid abnormality. Laboratory findings obtained from thorough adrenal hormonal excess investigation (ACTH, cortisol diurnal rhythm, ODST, aldosterone/PRA, DHEAs, 24 hrs urinary EPI/NOR/DOP) were reported as normal. The patient underwent laparoscopic left adrenalectomy. The intraoperative finding was suggestive to adrenal cyst. Histology of left adrenal mass showed the cyst 15 mm in diameter, with thyroid tissue inside cyst wall. Thyroid tissue had regular cellular characteristic and expressed TTF1, thyroglobulin, CK19, CK7, and PAX8 positivity. Whole body scan with I-131 performed postoperatively didn’t reveal any other additional sites of thyroid tissue.

Conclusion: We reported an exclusive case of ectopic thyroid tissue in the left adrenal cystic lesion.

Volume 70

22nd European Congress of Endocrinology

Online
05 Sep 2020 - 09 Sep 2020

European Society of Endocrinology 

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