ECE2020 Audio ePoster Presentations Reproductive and Developmental Endocrinology (79 abstracts)
1Medical University of Warsaw, Department of Internal Diseases and Endocrinology, Warsaw, Poland; 2The Centre of Postgraduate Medical Education, Department of Endocrinology, Warsaw, Poland
Background: Multiple Endocrine Neoplasia Type 1 (MEN1) is a rare, autosomal dominant disease characterized by the coexistence of at least two of the following: primary hyperparathyroidism (PHPT), neuroendocrine tumors (NET) and pituitary tumors. The aim of the study was to evaluate epidemiology, clinical features and management of MEN1 patients in two referral centers in Warsaw, Poland.
Material and Methods: Study group consisted of 52 patients, aged from 18 to 74 (mean: 45.5,
Results: In the studied group, the first symptoms of the disease appeared on mean age of 29.6 (range: 9–60;
Conclusions: In this group, MEN1 was diagnosed with a long delay from the disease onset. The discrepancy between number of women and men being followed-up may indicate its underdiagnosis in men. PHPT was proved to be the most difficult component to manage. Frequent coexistence of other tumors, both malignant and benign, has also been demonstrated. These results suggest a need for improvement at every level of healthcare, from detection to management.