ECE2020 Audio ePoster Presentations Pituitary and Neuroendocrinology (217 abstracts)
Endoscopic transsphenoidal pituitary surgery (ETPS) for pituitary tumors: Outcomes and complications
Eva Venegas-Moreno 1 , Pablo Remon 1 , Elena Dios-Fuentes 1 , Alejandro Deniz-Garcia 1 , Eugenio Cardenas 2 , Ariel Kaen 2 , Ignacio Martin-Schrader 2 , Natividad Gonzalez-Rivera 3 , Florinda Roldan 4 , David Cano-Gonzalez 5 & Alfonso Soto-Moreno 1
1Virgen del Rocio, UGC Endocrinology and Nutrition, Seville, Spain; 2Virgen del Rocio, UGC Neurosurgery, Seville, Spain; 3Virgen Macarena, UGC Endocrinology and Nutrition, Seville, Spain; 4Virgen del Rocio Hospital, UGC Radiology, Sevilla, Spain; 5IBIS, Seville, Spain
Methods: Restrospective descriptive study of patients who underwent ETPS for pituitary adenoma removal performed by the same surgical team in Virgen del Rocio Hospital of Seville from January 2014 to January 2019.
Results: 174 patients had a pituitary adenoma (44 GH, 36 ACTH, 94 Non functioning). 54.02% were female. In acromegaly, 39 (88.63%) patients were operated by ETPS as initial approach. 20 (51.28%) patients had cavernous sinus invation. At outcome analysis, 28 (71.19%) achieved biochemical and morphological remission; Cure rate was 100% for microadenomas, 67.66% for macroadenomas, 89.47% for non-invasive adenomas and 55% for invasive adenomas. Additionally, 5 patient with persistant disease after microscopic transsphenoidal surgery (MTS) were operated by ETPS, 3 (60%) were cured. 75 nonfunctioning adenomas were operated by ETPS as initial approach. After surgery, 46 (61.33%) were cured, with similar rates for invasive (59.57%), non-invasive (59.57%) adenomas and tumors larger than 25 mm (54.72%). 47 (62.67%) patients had visual impairment before surgery, 27 (57.44%) patients developed a full recovery after the surgery. 19 patients were operated by ETPS after unsuccessful MTS. Regrowth of pituitary remmant was observed in all reinterventions, 11 (57.89%) presented new campimetric deficits; after the intervention 6 (31.58%) reached cure criteria, with a cure rate for invasive adenomas of 33.33%; 10 (90.9%) presented full o partial recovery of visual impairment. 27 ACTH secreting adenomas were operated by ETPS by first time. After the surgery, 22 (81.48%) patients were cured. 9 patients were reoperated after an unsuccessful MPS, 6 (33.33%) were macroadenomas. 6 (66.67%) patients with a second operation were cured. Regarding complications, 2 patient had LCR fistula, 4 suspiction meningitis and 2 epistaxis.
Conclusions: The cure rates observed in our series were higher tan in the most MPS published series. Reintervention is an adequate treatment approach in cases of recurrence and resistant Cushing disease and Acromegaly.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more