Endocrine Abstracts

Introduction: Recent epidemiological surveys have demonstrated a significant association between MS and lower urinary tract symptoms (LUTS). The aims of this study were to determine LUTS in patients with metabolic syndrome (MS) and to evaluate their impacts in patients’ life quality.

Patients and Methods: A cross-sectional study was conducted on patients with metabolic syndrome MS diagnosed according to the criteria of the US National Cholesterol Education Programme Adult Treatment PanelIII (NCEP ATP III). Clinical evaluation included body mass index (BMI) and waist circumference measurement. Biological data were also collected including fasting blood sugar, postprandial glycemia, glycosylated hemoglobin (HbA1c), cholesterol and triglyceride levels. Lower urinary tract symptoms were assessed using the urinary symptom profile (USP) questionnaire and the impact in life quality was evaluated using Ditrovie score.

Results: Forty patients were collected with a mean age of 60.2 years (±10.5) and a sex-ratio of 0.5. All patients were diabetic and 62.5% had hypertension. The mean BMI was 26.6 ± 5.8 and waist circumference was 98.8 ± 8.3 cm. Mean USP total score was 11.1 ± 7.8. Overactive bladder symptoms were found in 60% of the patients, stress incontinence symptoms in 50% of the cases and dysuria in 22.5% of them. Mean Ditrovie score was 2.25. The USP total score wasn’t correlated to age (P = 0.07) nor to fasting blood sugar level (P = 0.89) nor to HbA1C level (P = 0.29). Ditrovie score was significantly correlated to the overactive bladder USP score (P = 0.014).

Conclusion: LUTS are frequent in patients with MS including meanly Overactive bladder symptoms and stress incontinence symptoms. Their impact in life quality is correlated to overactive bladder symptoms.