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Endocrine Abstracts (2020) 70 AEP449 | DOI: 10.1530/endoabs.70.AEP449

1Universidade Federal do Rio Grande do Sul, Endocrinology, Porto Alegre, Brazil; 2Hospital Escola UFPEL, Endocrinology, Pelotas, Brazil


Introduction: Chronic diseases such as type 1 diabetes can be associated with psychiatric disorders. Previous data suggest a high prevalence of depression, anxiety, disordered eating and diabetes distress among patients with diabetes. Mental health problems could interfere with treatment adherence, glucose control and chronic complications.

Objective: We aim to evaluate the prevalence of psychiatric disorders, drug abuse, and treatment adherence in patients with type 1 diabetes. We also aim to study the association of mental health problems with glycemic control and chronic complications.

Methods: A cross-sectional study was designed to apply face-to-face standardized questionnaires and to evaluate patients’ clinical data from medical records. We included patients with type 1 diabetes over the age of 10 who are assisted at two public hospitals linked to federal universities in Southern Brazil. Patients signed a consent form and the study was approved by Ethics Committee. We used Patient Health Questionnaire-2 (PHQ) and PHQ-9 to evaluate depression, Self Care Inventory-Revised to evaluate treatment adherence, and Eating Attitudes Test to study eating disorders. We also apply a questionnaire to investigate licit and illicit drugs use and anxiety symptoms.

Results: We included 166 patients with a median of 33 years (22–45 years), 53.6% were women, with a median of 14 years (6–25 years) since diabetes diagnosis, and a median of A1c of 8.5% (7.8–9.4%). 91 patients (54.8%) was diagnosed with one mental health disorders (20.5% of patients have depression and 40.4% have anxiety), and 79 (47.6%) patients had positive screening for eating disorder. About drug use, 16 (9.6%) patients are active smokers, 30 (18.1%) patients drink alcohol regularly, and 2 (1.2%) patients use illicit drugs. The comparison between patients with and without psychiatric illness showed a worse glycemic control in the group with mental disorder (A1c 9.0% vs 8.5% in controls); there was no other clinical or laboratorial difference between groups. Patients with suicidal ideation or attempt are almost entirely depressed (34 patients [94.4%]). 91 patients (54.8%) were considered to have good adeherence to treatment; this group of patients has a better A1c than non-adherent patients (8.4% vs 8.8%; P = 0.023).

Discussion: The prevalences of psychiatric illness, drug use and eating disorders are high among patients with type 1 diabetes and it is associated with a worse glycemic control. Clinical doctors should be aware of this scenario and, therefore, do screening for mental disorders in this population.

Volume 70

22nd European Congress of Endocrinology

Online
05 Sep 2020 - 09 Sep 2020

European Society of Endocrinology 

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