ECE2020 Audio ePoster Presentations Diabetes, Obesity, Metabolism and Nutrition (285 abstracts)
Predictors of metabolic disease in normal weight postmenopausal women: A cross-sectional study
Eleni Armeni 1 , Stavroula A Paschou 1 , Areti Augoulea 1 , Dimitrios Rizos 2 , George Kaparos 2 , Anastasia Palaiologou 2 , Anastasia Soureti 1 , Iliana Karagouni 1 , Michael Apostolakis 1 & Irene Lambrinoudaki 1
1Second Department of Obstetrics and Gynecology, Aretaieio Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece; 2Hormonal and Biochemical Laboratory, Aretaieio Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
Introduction: The aim of this study was to evaluate predictors of metabolic disease in normal weight postmenopausal women.
Patients and Methods: This cross-sectional study included 457 non-obese postmenopausal women, recruited from the Menopause Clinic of Aretaieio Hospital, National and Kapodistrian University of Athens. The diagnostic criteria of the International Diabetes Federation for the definition of Metabolic Syndrome were used, in order to classify women into metabolically healthy (<3 criteria, MHNW) and metabolically obese (≥3 criteria, MONW).
Results: Compared to the MHNW phenotype, MONW was positively associated with chronological age (58.9 ± 7.9 years vs 54.3 ± 6.6 years, P < 0.001), years since menopause (YSM, 12.4 ± 8.5 years vs 7.1 ± 6.2 years, P < 0.001), waist circumference (WC, 92.1 ± 6.6 cm vs 82.3 ± 8.4 cm, P < 0.001) and waist to hip ratio (WHR, 0.87 ± 0.06 vs 0.81 ± 0.08, P < 0.001). ROC curve analysis showed that WC represents a superior predictor of MONW compared with WHR (WC, AUC 0.815, 95% CI 0.773–0.858). Accordingly, WC of at least 86.5 cm predicted the MONW phenotype with sensitivity 72.7% and specificity 69.4%. Multivariate regression analysis showed that WC of at least 86.5 cm predicted the MONW phenotype in a model adjusted for age and YSM (OR 4.689, 95% CI 2.626–8.373, P < 0.001).
Conclusions: This study provided evidence that MONW women have increased chronological age and YSM compared with MHNW women. Metabolic disease can be predicted by a WC greater than 86.5 cm, irrespectively of age and YSM.
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more