Endocrine Abstracts

The aim of the study was to evaluate the risk of osteoporosis and related fractures in the patients treating in in-patient rehabilitation department.

Methods: The survey was conducted by means of questionnaire of 600 patients aged >50 y.o. ordinary treated in in-patient department of rehabilitation center. Risk factors for osteoporosis were assessed using IOF “One-minute osteoporosis risk test”. 10-year probability of major osteoporotic fracture was calculated using Russian scale of FRAX on-line calculator.

Results: Assessment of osteoporosis risk factors revealed that 58.2% of responders had no risk factors, 6.8% had one risk factor, 3.8% - two, 0.6% - three, 9.1% - four, 21.5% - five or more risk factors. 45.8% of responders had experienced non-traumatic fractures in past, and a fractures occurred during rehabilitation procedures in 4.6% of ones. High probability of major osteoporotic fracture was revealed in 38% of all respondents, in particular in 45.7% of women and in 16.6% of men. The average 10-years risk for major osteoporotic fractures was 13.7% [1.6; 48.0] and for the hip fracture - 3.2% [0;16]. 8.6% of patients had 10-year absolute risk for major osteoporotic fractures more than 30%. 42.5% of respondents performed bone densitometry in the past. Osteoporosis was already diagnosed in 34.1% of respondents but only in 56.6% (n = 127) of high fracture risk group. Among those who never undergo densitometry there were 43.1% of patients with a high fracture risk. Anti-osteoporoitic treatment received just 31.0% among osteoporotic patients and 12.4% among subjects with high fracture risk.

Conclusions: 45.7% of women and in 16.6% of men aged >50 y.o. ordinary treated in in-patient rehabilitation department have high risk of osteoporotic fracture, 41.2% patients had osteoporosis risk factors and 45.8% experienced non-traumatic fractures in past. Data indicate a high probability of non-traumatic fractures in those patients due to concomitant insufficient prescription of anti-osteoporotic medication.