EYES2019 7th ESE Young Endocrinologists and Scientists (EYES) Meeting Poster Presentations (46 abstracts)
Papillary thyroid carcinoma and Hodgkin Lymphoma in young patients – case report
Laura Cotoi 1 , Andreea Borlea 1 , Carmen Petrescu 2 , Crtistian Jinca 2 , Simona Cerbu 4 , Flore Varcus 4 , Marioara Cornianu 5 & Dana Stoian 6
1PhD Student,’ Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania; 2Department of Paediatrics III, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania; 3Department of Radiology, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania; 4Department of Surgery II, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania; 5Department of Morphopathology, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania; 6Department of Endocrinology, Department of Internal Medicine, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania.
Introduction: Differentiated thyroid cancer is one of the most common endocrine malignancies. The most common thyroid cancer in adolescence is PTC. It presents with a high rate of loco regional ganglionic metastasis. Hodgkin lymphoma (HL) is a heterogeneous group of neoplasms with an incidence, in Europe, estimated around 2.2–2.7 per 100 000 cases per year. In front of each adolescent case, with concomitant thyroid and lymph nodes, the main question that arises is the presence of intrathyroid lymphoma, PTC with ganglionic determination or the concomitance of two neoplastic tumors. The specialty literature recommends lymphoma approach with identification by biopsy of the cancer with the most malignant potential. In case of concomitance of lymphoma and thyroid cancer, thyroid treatment will be performed only after hematological stabilization.
Case presentation: Our paper presents the case of two adolescents with high risk on ultrasound thyroid lesions and concomitant lymph nodes. One patient has a history of treated Hodgkin Lymphoma and PTC after one year after lymphoma treatment, the other presents massive invasive lymphadenopathies from PTC.
Conclusion: Concomitant thyroid cancer and lymphoma is rare. The minimum time, in literature, between exposure to regional radiation and the occurrence of thyroid cancer, as the second cancer, is minimum 3 years, mean time 5–10 years. Whenever the concomitance of two cancers is probable, excluding lymphoma is the first necessary diagnostic and prognostic step, the oncologic benefit surpassing the surgical radicality.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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