Endocrine Abstracts

Contents

• 47th Annual Meeting of the British Society for Paediatric Endocrinology and Diabetes 2019
• • CME TRAINING DAY SESSIONS
  • Session 1
  • • Abstract unavailable

      ea0066cme1.1
    • Talking to children about sex development

      ea0066cme1.2
  • Session 2
  • • Recognition and assessment of pituitary tumours: what the clinician needs to know

      ea0066cme2.1
    • Paediatric vulval disorders

      ea0066cme2.2
  • Session 3
  • • Challenges in the management of the SGA child

      ea0066cme3.1
    • The pituitary - growth hormone deficiency and beyond

      ea0066cme3.2
  • Session 4
  • • Diabetes technology update (CME lecture)

      ea0066cme4.1
    • Abstract unavailable

      ea0066cme4.2
• MAIN SYMPOSIA
• • Endocrine Track 1: Symposium 1
  • • Long-term outcomes for young women with PCOS

      ea0066s1.1
    • Abstract unavailable

      ea0066s1.2
    • Maternal thyroid function in pregnancy and childhood outcomes

      ea0066s1.3
  • Endocrine Track 1: Symposium 2
  • • Abstract unavailable

      ea0066s2.1
  • Diabetes Track 1: Symposium 3
  • • Abstract unavailable

      ea0066s3.1
    • Role of the enviroment in the pathogenesis of type 1 diabetes

      ea0066s3.2
    • Newer treatments for type 2 diabetes in children

      ea0066s3.3
  • Diabetes Track 1: Symposium 4
  • • Abstract unavailable

      ea0066s4.1
    • QI in action - the Sheffield Children's Hospital experience

      ea0066s4.2
    • Improving diabetes care: lessons from registries

      ea0066s4.3
  • Nurses' Day for Endocrine Professionals: Symposium 5
  • • Abstract unavailable

      ea0066s5.1
    • Congenital TSH deficiency

      ea0066s5.2
    • Abstract unavailable

      ea0066s5.3
• DEBATE: SPEAKER BIOGRAPHIES
• • (1)
  • • Abstract unavailable

      ea0066d1.1
    • Abstract unavailable

      ea0066d1.2
• INQUISITOR SESSION: SPEAKER BIOGRAPHIES
• • (1)
  • • Abstract unavailable

      ea0066in1.1
    • Abstract unavailable

      ea0066in1.2
• PENS PRESENTATION
• • (1)
  • • The evolving role of the children's endocrine nurse specialist

      ea0066pens1.1
    • Abstract unavailable

      ea0066pens1.2
    • Patients living with CAH

      ea0066pens1.3
• DIABETES PROFESSIONALS' DAY SESSIONS
• • Session 1
  • • Nutrition, food science and cooking - what role in management of diabetes in children?

      ea0066ds1.1
    • Using Carbs & Cals in everyday everyday practice

      ea0066ds1.2
    • Practical diabetes - disordered eating and type 1 diabetes

      ea0066ds1.3
  • Session 2
  • • Abstract unavailable

      ea0066ds2.1
    • Avoiding hypoglycaemia during sporting activity

      ea0066ds2.2
  • Session 3
  • • Getting the best out of social media in paediatric diabetes

      ea0066ds3.1
    • Type 2 diabetes, an increasing problem: lessons from national surveys

      ea0066ds3.2
• NURSES' DAY FOR ENDOCRINE PROFESSIONALS SESSIONS
• • Session 1
  • • Abstract unavailable

      ea0066nd1.1
    • Abstract unavailable

      ea0066nd1.2
    • Abstract unavailable

      ea0066nd1.3
  • Session 2
  • • Assessing and monitoring growth in children with bone disorders

      ea0066nd2.1
    • Abstract unavailable

      ea0066nd2.2
• ORAL COMMUNICATIONS
• • Oral Communications 1
  • • Exploring trends in the glucocorticoid and mineralocorticoid treatment of congenital adrenal hyperplasia by analysing data from the I-CAH registry

      ea0066oc1.1
    • Pituitary Apoplexy in an adolescent male with Macroprolactinoma presenting as middle cerebral artery infarction

      ea0066oc1.2
  • Oral Communications 2
  • • National United Kingdom evidence- and consensus-based guidelines for the investigation, treatment and long-term follow-up of paediatric craniopharyngioma

      ea0066oc2.1
    • A rare but very important cause of growth failure

      ea0066oc2.2
  • Oral Communications 3
  • • Using quality improvement methods to enhance HbA1c outcomes for newly diagnosed children and young people with diabetes

      ea0066oc3.1
    • 2 year experience of 'Do-It-Yourself ' Hybrid Closed Loop in an adolescent with Type 1 Diabetes

      ea0066oc3.2
  • Oral Communications 4
  • • Mortality after childhood growth hormone treatment in the UK - the SAGhE study

      ea0066oc4.1
    • Burosumab initiation in a UK XLH cohort: real-world use resonates with research evidence

      ea0066oc4.2
    • Defects in LGR4 Wnt-[beta]-catenin signalling impair GnRH network development, leading to delayed puberty

      ea0066oc4.3
    • A novel clinical risk score that accurately predicts recurrence of craniopharyngioma - a multicentre cohort study

      ea0066oc4.4
    • Novel genetic defects in a cohort of Silver-Russell Syndrome (SRS) and SRS-like patients

      ea0066oc4.5
    • Understanding differences of sexual differentiation (DSD) MDT services across the UK; current service provision and sharing best practice

      ea0066oc4.6
    • Novel variants in the Leucine-zipper-like transcription regulator 1 (LZTR1) gene cause Noonan syndrome phenotype by upregulation of the RAS-MAPKinase pathway

      ea0066oc4.7
    • SGPL1 deficiency leads to accumulation of sphingolipid species and downregulation of key enzymes within the steroidogenic pathway

      ea0066oc4.8
    • Health status of children aged 8-18 years with 21-hydroxylase deficiency in the United Kingdom: results of a multi-centre cohort study

      ea0066oc4.9
  • Oral Communications 5
  • • Project to develop BSPED UK standardised guidelines for sex hormone priming and glucagon stimulation testing (GST) in children and adolescents

      ea0066oc5.1
    • Longitudinal outcomes of well, term infants who present with persistent hyperthyrotropinaemia

      ea0066oc5.2
    • Causes of central diabetes insipidus in children: a single-centre experience

      ea0066oc5.3
    • Tolvaptan for hyponatraemia in infants with brain tumours

      ea0066oc5.4
    • Recombinant human Insulin-like growth factor-1 (rhIGF-1) therapy: a 15-year experience in a tertiary care centre

      ea0066oc5.5
    • Monitoring and long-term disease activity in children with X-linked hypophosphataemia on conventional therapy

      ea0066oc5.6
    • Longitudinal changes in external masculinisation scores in boys born with XY disorders of sex development

      ea0066oc5.7
    • TSH-Receptor testing in pregnancy allows stratification of risk of neonatal thyrotoxicosis and promotes earlier discharge

      ea0066oc5.8
    • Rare causes of primary adrenal insufficiency (PAI) in children from Sudan

      ea0066oc5.9
    • Review of neonatal cortisol evaluation between 2012-2018 in a single centre: trends, outcomes and associations

      ea0066oc5.10
  • Oral Communications 6
  • • A survey into the care of children with type 2 diabetes in England and Wales

      ea0066oc6.1
    • An exploration of the perceptions and lived experience of primary school aged children using insulin pump therapy

      ea0066oc6.2
    • Here's the POInT: a multicentre European Primary Oral Insulin Trial

      ea0066oc6.3
    • Exam preparedness in students with type 1 diabetes and their schools - a quality improvement study

      ea0066oc6.4
    • Factors affecting the practice of routinely downloading blood glucose data at home for families and children with type 1 diabetes

      ea0066oc6.5
  • Oral Communications 7
  • • Increased and younger alcohol-related hospital admissions in young people with childhood-onset type-1 diabetes: a record-linked longitudinal population study in Wales

      ea0066oc7.1
    • Impact of continuous glucose monitoring on sleep quality in children with type 1 diabetes and their parents: a pilot study

      ea0066oc7.2
    • Improving HbA1c outcomes in young people of transition age with type 1 diabetes using quality improvement methodology

      ea0066oc7.3
    • Monitoring lipid profiles in children and young people with type 1 diabetes mellitus: what should we do with these results?

      ea0066oc7.4
    • Medication adherence during adjunct therapy with statins and ACE inhibitors in adolescents with type 1 diabetes

      ea0066oc7.5
    • Improving referral pathways from primary to secondary care in newly diagnosed type 1 diabetes

      ea0066oc7.6
    • Paediatric Type 2 diabetes in a single centre in East London in the period 2009-2018

      ea0066oc7.7
    • Children with type 1 diabetes on intensive insulin, in deprived areas and younger onset are at risk of being overweight

      ea0066oc7.8
    • Does having a first degree relative with type1 diabetes impact on a child and family's engagement and glycaemic control?

      ea0066oc7.9
  • Oral Communications 8
  • • Random cortisols - as useful as a chocolate teapot (but less tasty)?

      ea0066oc8.1
    • Adrenal Insufficiency: hydrocortisone prescribing and sick day rules

      ea0066oc8.2
    • Specially identified patients (SIPs) - how do they work?

      ea0066oc8.3
    • Optimising transition care in endocrinology: an example of patient-focused quality improvement

      ea0066oc8.4
    • The impact of Prader-Willi syndrome multidisciplinary clinic on growth parameters

      ea0066oc8.5
• Poster Presentations
• • Adrenal, Gonadal, DSD and Reproduction, and Basic Science
  • • Learning from clearance studies, 24 h profiling and pump therapy - PUTTING the onus on cortisol replacement rather than 17OHP and androstenedione

      ea0066p1
    • Variations in 17[alpha]-hydroxyprogesterone response to hydrocortisone treatment for congenital adrenal hyperplasia in children

      ea0066p2
    • Non classical congenital adrenal hyperplasia presenting with a severe salt losing crisis

      ea0066p3
    • A regional service for children and young people with familial hypercholesterolaemia: lessons learnt

      ea0066p4
    • Optimisation of transfection methods using various formats of gRNA delivery for CRISPR Cas9 mediated gene knock out in Beta-TC-6 cells

      ea0066p5
    • Improving midwives' recognition of atypical genitalia and differences of sexual development (DSD) through the use of an e-learning module

      ea0066p6
  • Bone
  • • Burosumab experience in UK XLH children under five years old

      ea0066p7
    • Clinical, functional and quality of life outcomes of Burosumab therapy in children with X-linked hypophosphoataemia: a real world, London experience

      ea0066p8
    • Evidence for association of PTEN-harmatoma-tumor syndrome with osteosarcoma

      ea0066p9
    • Vitamin D levels of mothers with and without vitamin D supplementation in pregnancy and their newborns

      ea0066p10
    • Hypercalcaemia as a presenting feature of sarcoidosis: the need for an open mind

      ea0066p11
    • Vitamin D dependent rickets

      ea0066p12
    • Dental manifestations of vitamin D deficiency in adolescents

      ea0066p13
    • A novel case report of severe hypercalcaemia occurring after four years on the ketogenic diet

      ea0066p14
    • Not your typical rickets case

      ea0066p15
  • Diabetes 1
  • • Improving the rate of completion of 7 care processes at a busy district general hospital by using quality improvement methodology

      ea0066p16
    • The hospital school as a resource for supporting children with type 1 diabetes during planned admissions

      ea0066p17
    • Botswana children and young people with diabetes partnership project

      ea0066p18
    • Diasend download data and relation to diabetes control in a tertiary clinic cohort

      ea0066p19
    • Identifying barriers and solutions to the optimal management of a patient with T1DM and a severe life limiting dermatological condition

      ea0066p20
    • Will informing patients with diabetes about their care processes results help improve care processes completion rates? An innovative project

      ea0066p21
    • Group outpatient clinics for children and young people with type 2 diabetes: a service evaluation

      ea0066p22
    • Different financial models employed by diabetes transition units within Yorkshire and South West London's Children and Young People's (CYP) networks

      ea0066p23
  • Diabetes 2
  • • Characterizing putative mutant variants of monogenic diabetes

      ea0066p24
    • Modifiable dietary factors and a case for tracking dietetic outcomes in the National Paediatric Diabetes Audit

      ea0066p25
    • Two cases of bilateral cataracts in early type 1 diabetes

      ea0066p26
    • Observational Study looking at the Impact of changing from novorapid to insulin aspart on glycaemic control in the clinic setting

      ea0066p27
    • Using quality improvement (QI) to improve the care pathway and outcomes for children newly diagnosed with type I diabetes mellitus

      ea0066p28
    • Bridging the gap: a young person-centred diabetes transition service

      ea0066p29
    • Perceptions of multi-disciplinary team members and their roles: a survey of 82 carers and patients

      ea0066p30
    • Continuous glucose monitoring improves A1c, time in hypoglycaemia and time spent in target range within the paediatric population

      ea0066p31
  • Diabetes 3
  • • Development of a live visual HbA1c dashboard to improve engagement and clinical outcomes - a type 1 diabetes QI project

      ea0066p32
    • C-peptide and antibody testing to aid diabetes diagnosis in children and young people

      ea0066p33
    • When one diagnosis just isn't enough - diabetes as a first presentation of cystic fibrosis

      ea0066p34
    • Rare association of type 1 diabetes mellitus (T1DM) with tubulo-interstitial nephritis and uveitis (TINU) and hypercalcaemia

      ea0066p35
    • Using NPDA data for quality improvement: dedicated annual review clinics are effective in increasing completion rates of health care processes

      ea0066p36
    • Improving outcomes for young people with type 2 diabetes mellitus

      ea0066p37
    • Remission rates, demographics and outcomes of paediatric patients with type 2 diabetes at a single centre: 2006-2018

      ea0066p38
    • Paediatric diabetic ketoacidosis (dka)-management in a district general hospital

      ea0066p39
  • Diabetes 4
  • • Neonatal diabetes, Don't sugar coat it!

      ea0066p40
    • Young person with Prader-Willi syndrome and type 2 diabetes - management challenges

      ea0066p41
    • Newly diagnosed diabetes - incidence, presenting features and lessons learnt

      ea0066p42
    • Continuous glucose monitoring/flash glucose monitoring in type 1 diabetes. Local unit experience at Glan Clwyd Hospital, Wales

      ea0066p43
    • Treatment of paediatric diabetic ketoacidosis (DKA) with subcutaneous rapid-acting insulin: a UK centre, retrospective review of safety and efficacy data

      ea0066p44
    • Practical application and user experience of flash glucose monitoring in paediatric patients with type 1 diabetes

      ea0066p45
    • A regional UK audit between 2010-2018 of national quality indicators and surveillance of staffing levels in paediatric diabetes care units

      ea0066p46
    • Patient directed carbohydrate counting from diagnosis - the Torbay experience

      ea0066p47
  • Diabetes 5
  • • A rare complication of diabetic ketoacidosis: spontaneous pneumomediastinum with subcutaneous emphysema

      ea0066p48
    • Paediatric random glucose requests in primary care

      ea0066p49
    • Use of flash glucose monitoring during hypo/hyperglycaemia and to guide insulin administration in paediatric patients with type 1 diabetes

      ea0066p50
    • A qualitative study evaluating solution focus brief therapy in improving delivery of diabetes care by healthcare professionals

      ea0066p51
    • A case of ischaemic stroke associated with severe DKA

      ea0066p52
    • Review of compliance and methods of carbohydrate counting in paediatric diabetic patients at District General Hospital

      ea0066p53
    • A case of prolonged partial remission of type 1 diabetes

      ea0066p54
    • Iatrogenic cardiac arrest and severe neurological complications in DKA (diabetic ketoacidodis)

      ea0066p55
  • Diabetes 6
  • • Assessing the impact of continuous glucose monitoring (CGM) and flash glucose scanning (FGS) on HbA1c levels in paediatric diabetic patients

      ea0066p56
    • A retrospective audit comparing diabetes control during summer and winter, in children with type 1 diabetes

      ea0066p57
    • Quality improvement project assessing effect on diabetes control from the introduction of an empowerment tool to facilitate insulin self adjustment

      ea0066p58
    • Audit on paediatric type 1 diabetes patients with HbA1c elevated >75 mmol/mol at a North West District General Hospital

      ea0066p59
    • Audit on the management of diabetic ketoacidosis in children in 2 District General Hospitals: creation of a DKA pathway

      ea0066p60
    • Our diabetes quality improvement initiative journey - ensuring an efficient and purposeful clinic experience…

      ea0066p61
    • Boy with type 1 diabetes and chronic idiopathic pancreatitis secondary to heterozygous variance for SPINK 1G

      ea0066p62
  • Learning from Mistakes and Miscellaneous
  • • The use of 'Hypopaks' in the investigation of hypoglycaemia in children

      ea0066p63
    • 'Cognitive Bias - One of many'

      ea0066p64
    • Perplexing presentation of hypoglycemia

      ea0066p65
    • [beta]-carotenaemia with secondary amenorrhea in a teenage athlete

      ea0066p66
    • Using CRISPR/Cas9 gene editing to study the molecular mechanisms of congenital hyperinsulinism (CHI)

      ea0066p67
    • Mitochondrial disorders and endocrine dysfunction

      ea0066p68
    • Improving the patient journey in the children and young people diabetes clinics of the Cardiff and Vale Health Board

      ea0066p69
    • Audit of annual review investigations for girls with Turner's syndrome against the Turner's syndrome support society checklist

      ea0066p70
    • Intracranial hypertension secondary to severe obesity: case series

      ea0066p71
  • Pituitary
  • • Real-world safety data in children with Noonan syndrome treated with growth hormone: results from NordiNet®IOS and the Answer^®Program

      ea0066p72
    • Three novel Growth Hormone Receptor (GHR) splicing mutations causing a spectrum of Growth Hormone Insensitivity

      ea0066p73
    • STAT5B missense variant causing growth hormone deficiency with subclinical hypothyroidism and immune deficiency in a 13-year-old female: a case report

      ea0066p74
    • Growth and growth hormone abnormalities in bartter syndrome types 3 and 4

      ea0066p75
    • A new frameshift mutation in immunoglobulin superfamily, member 1 (IGSF1) results in central hypothyroidism, delayed puberty and GH deficiency

      ea0066p76
    • Observed effects of growth hormone doses on height in patients with Prader Willi Syndrome

      ea0066p77
    • Cranial diabetes Insipidus and anterior pituitary hormone deficiencies following 'minor' concussive sports head injury

      ea0066p78
    • A case of 17 years old beta thalassaemic boy with polyendocrinopathy secondary to hemosiderosis

      ea0066p79
  • Thyroid
  • • Incomplete isosexual precocious puberty with macroadenoma: a rare presentation of primary hypothyroidism (Van Wyk-Grumbach Syndrome)

      ea0066p80
    • The neonatal screen that cried Wolff

      ea0066p81
    • Siblings with multinodular goiter and autoimmune thyroiditis

      ea0066p82
    • Congenital hypothyroidism: screening, diagnosis, treatment & follow up - evaluation of service provided in a District General Hospital

      ea0066p83
    • Deficiency of vitamin D as a potential factor of the development of Graves' disease in children and adolescents

      ea0066p84
    • Paediatric Graves disease - management in a District General Hospital

      ea0066p85