ea0064003 | Impact of changes in muscle secretome in the improvement of glucose homeostasis induced by bariatric surgery | BES2019
Orioli L
, Szczerbak M
, Navez B
, Lause P
, de Barsy M
, Loumaye A
, Deswysen Y
, Thissen JP
Introduction: Type 2 diabetes results from insulin resistance and B-cell failure. Bariatric surgery is an effective therapeutic modality for type 2 diabetes. Indeed, it induces high remission rates through improved insulin sensitivity and secretion. While the critical role of skeletal muscle in glucose homeostasis has long been known, its role as an endocrine organ secreting peptides, called myokines, has recently been identified. Some of these myokines were shown to influence...