Endocrine Abstracts

Early diagnostics it is IPA treats difficult questions of a modern neuroendocrinology as even highly informative computer tomographs and the magnetic resonant imaging (MRI) don’t give the correct answer to 30–55% of cases, and at microadenomas to 90% of cases.

The purpose: Studying of structure it is IPA at MRI-research at patients with the verified diagnosis.

Material and methods: Research included 325 patients with is IPA (145 women and 180 men at the age of 18 till 70 years (44.5±3.85 years). Middle age of 15–70 (43.6±3.84) years. Disease duration from the moment of establishment of the diagnosis on the basis of the anamnesis and MRI-researches from 1 year to 15 years.

Results and discussion: The studied patients had adenomas with intrasellar – 74, parasellar – 41, infrasellar – 23, infraparasellar – 26, suprasellar – 14, supraparasellar – 25, suprainfrasellar – 13, suprainfraparasellar – 12, suprainfrapararetrosellar distribution – 97. At MRI – research structure it is IPA had mainly soft tissue (n=269) and a cystic (n=56) structure. In 55 cases structure it is IPA was it is presented by a hemorrhagic component, and at 12 from them there were both cystic and hemorrhagic components. In 271 cases the structure of a tumor was rather uniform, in 54 – non-uniform. MRI of the image of 54 patients with is IPA had a hypointensive signal on T1-and an isointensive signal on the T2-weighed images, 204 cases were hypointensive and on T1-and on the T2-weighed images, 28 tumors were hypointensive on the T1-weighed images and hyperintensive on the T2-weighed images, 11 cases were izointensivna on the T1-weighed images and hypointensive on the T2-weighed images, and 9 cases – izointensive on the T1-weighed images and hyperintensive on the T2-weighed images.

Conclusions: Thus, at MRI research the majority it is IPA had intrasellar (29.8%) and suprainfrapararetrosellar (19.7%) distribution, in 82.8% of cases — solid structure, in 7.7% – contained cystic inclusions, in 9.5% – a hemorrhagic component contained. The MR-signal from the IPA tissue is predominantly hypointensive, as on the T2-weighed images (66.2%), and T1-weighed images (88.0%). Difference on MR-images depending on the sizes and from extent of distribution it is IPA are not revealed.