Endocrine Abstracts

Abstract: Parathyroid gland adenoma is benign, PTH-secreting tumour, which leads to primary hyperparathyroidism. Congenital hyperparathyroidism may occur without any other symptoms, on it’s own, but often is part of MEN1 or MEN2 syndromes. PTH activates osteoclasts, that resorbs calcium from bone and brings calcium to blood serum. Also PTH also induces calcium reabsorption from kidney tubules band and blocks excretion of phosphates. Long time PTH secreting adenoma shows no clinical signs, often adenoma is diagnosed only when complications are present. We describe the case of a patient who had parathyroid gland adenoma, that manifested like acute pancreatitis. 58 y/o female applied to the family doctor for weakness, abdominal pain, nausea, vomiting. After eveluation of primary blood tests, hypercalcemia, elevated PTH levels were present, more diagnostic tests were performed. Parathyroid gland adenonoma was found in left lobe and a left inferior parathyroidectomia was performed. After operation, patients calcium and PTH levels normalized. Investigating patients with gastrointestinal tract pathology, especially those, who have acute pancreatitis, without anamnesis of other, more common causes (eg. alcoholism, gallstones etc.) calcium test should be considered, becouse primary hyperparathyroidism may manifest as acute pancreatitis.