Endocrine Abstracts

Introduction: PCOS is the most common female endocrine disorder with a prevalence of approximately 5–10% in women of reproductive age. PCOS includes hyperandrogenic features, infertility and insulin resistance among others. Lately, Vitamin D has been involved in the etiology of various disorders.

Objective: The aim of our study is to define the role of vitamin D as an etiological and predictive factor in PCOS.

Materials and methods: The study comprises 25 cases of PCOS diagnosed on the basis of Rotterdam criteria. The parameters assessed include HOMA-IR, vitamin D besides the routine anthropometric and biochemical parameters.

Results: The study population was divided into 3 groups according to vitamin D status. Insulin resistance was most severe in the sub group with vitamin D deficiency.

Conclusion: Vitamin D has an important role in the pathogenesis of insulin resistance in PCOS.

Keywords: vitamin D, insulin resistance, polycystic ovarian syndrome