Endocrine Abstracts

Objective: To study the quality of life in women of reproductive age with different phenotypes of polycystic ovarian syndrome (PCOS).

Materials and methods: 68 women with diagnosed polycystic ovarian syndrome aged 18–44 and 30 practically healthy women of the comparable age. According to the patient’s phenotype the main group was divided into 2 subgroups: patients with PCOS and obesity of varying severity (BMI> 25 kg/m²) and patients with PCOS and normal body weight (BMI<25 kg/m²). The quality of life was assessed with the use of SF-36 questionnaire.

Results and discussion: The average figures for the mental health component in patients with PCOS in group I were 59.25±5.1 points; in group II they were 63.25±3.4 points and were significantly lower compared to the figures in practically healthy individuals — 91.66±4.3 points. The average figures for the physical health component (PH) in patients with PCOS in group I were 69.25±4.7 points; in group II they were 73.25±4.3 points and were also significantly lower compared to the figures in practically healthy individuals −96.66±1.4 points.

Conclusion: The obtained results indicate a decline in the quality of life indicators in women of reproductive image with PCOS and obesity of varying severity. It has been found that in patients with PCOS and obesity, both the physical and psychological components of health are affected. But the psychological component plays a more prominent role in the quality of life of the patients in the study group.