Endocrine Abstracts

Abstract Unavailable....

Craniopharyngiomas are surgically challenging brain tumors. Postoperatively, quality of life is often significantly impaired due to neurological and endocrinological complications. Currently, FDA approved systemic treatments are not available for patients in whom craniopharyngiomas recur after surgery and radiation. Papillary craniopharyngiomas are characterized by the presence of BRAFV600E mutations. In this presentation, the authors generate an o...

When a craniopharyngioma (CP) causes hypothalamus (HT) damage this will result in hypothalamic obesity (HO), cognitive dysfunction and increased stroke mortality. Suggested treatment when the HT is affected by a CP is subtotal resection and in some cases followed by cranial radiotherapy (CRT). In the preoperative phase, a multidisciplinary team may suggest HT sparing surgery with subtotal tumour removal. If in spite of all efforts the HT is damaged, there will be an immediate ...