ECE2019 Poster Presentations Thyroid 3 (74 abstracts)
Goiter and hashimoto’s thyroiditis
Ifigenia Kostoglou-Athanassiou 1 , Lambros Athanassiou 2 , Eleni Xanthakou 3 , Panagiotis Spyropoulos 4 , Athanasios Fortis 5 , Charilaos Samaras 2 , Paraskevi Potamousi 2 & Panagiotis Athanassiou 6
1Department of Endocrinology, Asclepeion Hospital, Voula, Athens, Greece; 2First Department of Medicine, Asclepeion Hospital, Voula, Athens, Greece; 3Endocrinologist, Sparti, Greece; 4Endocrinologist, Athens, Greece; 5Second Department of Medicine, Asclepeion Hospital, Voula, Athens, Greece; 6Department of Rheumatology, St Paul’s Hospital, Thessaloniki, Greece.
Introduction: Hashimoto’s thyroiditis is known to induce nodularity in the thyroid and in some cases to coexist with papillary thyroid carcinoma. However, the effect of the development of Hashimoto’s thyroiditis on the course of nodular goiter is not known.
Aim: The aim was to describe the effect of the development of Hashimoto’s thyroiditis in the course of nodular goiter.
Methods: A cohort of 12 patients, female, aged 22 to 50 years old is described. The patients presented with nodular goiter. The goiter was not causing obstructive symptoms, the patients being followed up. In the course of the disease they developed antithyroid antibodies, anti-thyroglobulin and anti-thyroid peroxidase antibodies. The patients developed overt hypothyroidism over a period of 2–5 years.
Results: Thyroxine was administered for the treatment of hypothyroidism. Three years after the development of hypothyroidism the patients were evaluated. Ultrasound examination revealed the absence of nodules within the thyroid gland. In 3 of the patients the thyroid was smaller than normal while in the rest of the group the thyroid was of normal size.
Conclusions: Goiter is known to be associated with iodine deficiency, on the contrary Hashimoto’s thyroiditis being associated with iodine sufficiency. Iodine sufficiency seems to have altered the epidemiology of thyroid disease. In the present study we report the effect of the development of Hashimoto’s thyroiditis on thyroid nodularity in a cohort of female patients. It appears that the development of Hashimoto’s thyroiditis, overt hypothyroidism and the subsequent treatment with thyroxine may modulate thyroid nodularity.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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