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Endocrine Abstracts (2019) 63 P1184 | DOI: 10.1530/endoabs.63.P1184

ECE2019 Poster Presentations Thyroid 3 (74 abstracts)

Screening of thyroid dysfunction in diabetic pregnant women

Sara Atraki , Siham El Aziz , Selma Bensbaa & Asmaa Chadli


Endocrinology, Diabetology and Metabolic Diseases Department Ibn Rochd University Hospital of Casablanca, Morocco, Neurosciences and Mental Health Laboratory Faculty of Medicine and Pharmacy- University Hassan II, Casablanca, Morocco.


Introduction: Thyroid disorders are quite common during pregnancy complicated by diabetes mellitus.

Objective: The aim of our study was to detect thyroid disorders in a group of diabetic pregnant women.

Patients and methods: Rétrospective study involving 243 pregnant women with diabetes followed in consultation or hospitalized in Endocrinology and Diabetology department of Ibn Rochd University Hospital of Casablanca, over a period from January 2016 to Octobre 2018. Data collection was done from medical records. All women had been interrogated for personal and family history of dysthyroidism and a complete physical examination. They had benefited from a biological assessment including the couple FT4-TSH. The evaluation of thyroid status referred to the 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum.

Résults: Mean age of women was 32 years old (18–49). They have on average 4 gestations, 2 parities and 2 live children. 36.6% of patients had gestational diabetes and 63.6% had pre-gestational diabetes (43.62% type 2 diabetes, 19.75% type 1 diabetes). The average term at first consultation was 21.6 weeks of amenorrhea (5–37): 49.5% were in the first trimester of pregnancy while 37.7% and 12.6% were respectively in the 2nd and 3rd trimester. The average TSH was 1.44±0.96 uIU/mL (0.28–5.28) while FT4 was 11.35±1.94 pmol/l (6.16–15.74). 25.10% of women suffered from some form of thyroid disorder, mostly (55.73%) hypothyroidism. Thyroid dysfunction was not associated with the type of diabetes mellitus (GDM or PGDM) (P<0.05). Nearly half of these patients had been put on L-thyroxine. This treatment was recommended in patients with a thyrotropin level higher than 2.5 mui/l. Hyperthyroidism was noticed in 44.26% of our patients and was dominated by gestational transient thyrotoxicosis (62.96%).

Conclusion: The study findings warrant routine screening for thyroid abnormalities in diabetic pregnant women. These women have increased rate of maternal and neonatal complications.

Volume 63

21st European Congress of Endocrinology

Lyon, France
18 May 2019 - 21 May 2019

European Society of Endocrinology 

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