ECE2019 Poster Presentations Thyroid 2 (70 abstracts)
Is repeat fine needle aspiration required in thyroid nodules with initial benign cytology?
Hafiz Muhammad Zia-Ul-Hussnain , Mark Quinn , Emma Dolan , Mark Sherlock , Chris Thompson , Diarmuid Smith , James Paul O’Neill , Mary Leader , Helen Barrett , Arnold Hill , Martina Morrin , Cliona Ryan & Amar Agha
Beaumont Hospital, Dublin, Ireland.
Background: Fine needle aspiration (FNA) is the preferred method for assessing thyroid nodules but concern remains about false negative results. The primary aim of this study was to investigate the malignancy rate in nodules which were initially classified as benign (BTA classification Thy 2). The secondary aim was to look at the distribution of different cytological categories in a large cohort of patients.
Methods: We retrospectively examined 719 nodules in 714 patients between 2013 to 2017. All FNAs were performed under US guidance. Nodules were cytologically classified according to the BTA guidelines. 53% of nodules were either followed up by ultrasonography or repeat FNA and rest were followed up clinically. Decision regarding follow up was done at a multidisciplinary meeting (MDM). Patients were followed for a median of 48 months.
Results: 604(84.5%) patients were female.558 nodules (77.6%) were classified as benign (thy2), 82 (11.1%) were thy1,52 (7.2%) were Thy3.6 (0.8%) were Thy4 and 15 (2.0%) were Thy5. Five Thy 2 nodules (0.89%) were later diagnosed with thyroid cancer of which one had low initial cellularity, one was a co-incidental microcarcinoma in a colloid nodule and one was a cystic papillary carcinoma. All 5 were in remission following treatment with surgery ± radioiodine therapy.
Conclusion: The false negative rate of initial benign FNA is very low in our cohort so routine second FNA is not required in these patients. MDM is useful in informing decision making in those patients
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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