Endocrine Abstracts

According to state statistics service, Russia’s population in 2018 is more than 146.8 mil people. The total prevalence of acromegaly may range between 2.8 and 13.7 cases per 100,000 people and the annual incidence rates vary between 0.2 and 1.1 cases per 100,000 people (Lavrentaki A, et al. 2016). The epidemiological data for acromegaly in Russian population is lacking. The Russian hypothalamic and pituitary tumors registry was founded in 2004 and for 2018 it contains the medical data of 8543 patients, among them – 4076 patients with acromegaly. Our aim was to compare the epidemiological data from Russian hypothalamic and pituitary tumors registry with the calculated prevalence and incidence rates. According to the database, highest prevalence of acromegaly is registered in Kirov federal subject – 8.7 per 100 000 people, Penza federal subject – 7.5 per 100,000 people and in Krasnoyarsk federal subject −7.2 per 100,000 people. The prevalence in these regions is within the predicted range. However, other federal subjects show significantly less prevalence of the disease. Moreover, not all of the regions participate in the registry. According to the previously mentioned data, the calculated amount of patients with acromegaly could vary from 4110 to 20112 cases and the annual incidence rate from 293,6 to 1614,8 cases. For the 2017 and 2018, there were 107 and 37 new registered cases of acromegaly added to the registry, respectively. The number of patients in the registry is lower than the population-based calculated values. This could be attributed to the fact that not all of the regions participate in the registry and even in participating regions there is a probability of missing the data due to human factor or lack of communication between health care centres. These data suggest that more effort should be put in order to establish health care continuity to ensure the high quality of epidemiological registry-based data.