Endocrine Abstracts

Introduction: The pituitary adenoma is a benign hyperplasia of the pituitary gland; it often implies the presence of pathologies of the thyroid gland. The relation between the thyroid volume, the rate of IGF1 and the duration of the disease is not well specific, long time the secretion of GH and IGF1 have been associated with disorders of thyroid function.

Presentation of the case: We report the observation of a 37-year-old woman operated on in 2016 with a transphenoidal pituitary macro-adenoma with regression of the tumor and a left loboisthmectomy of a diving goiter classified papillary carcinoma. It should be noted that the level of IGF1 remained constant at twice normal despite surgery. The patient received a Levothyrox-based treatment. She represents for headaches with BAV, the pituitary MRI performed notes an upsurge of the pituitary adenoma and in parallel a recurrence at the level of loboisthmectomy stump and also a right thyroid nodule classified TIRADS 4. The assessment of neuroendocrine tumors is negative. The rate of thyroglobulin is increasing, four times more than 2 years ago. A second revision is planned in our patient with monitoring of thyroid function.

Conclusion: Although data on the coexistence of acromegaly and thyroid cancer remain controversial, it is important to diagnose early stage disease, eliminate thyroid cancer, and follow-up with careful evaluation of thyroid cancer. thyroid function to prevent recurrence. Also the upsurge of these two tumors can be explained by the high rate of IGF1.