ECE2019 Poster Presentations Diabetes, Obesity and Metabolism 3 (112 abstracts)
Neuroimaging in the diagnosis of neuroplasticity in patients with diabetes mellitus
Mariia Matveeva 1 , Natalie Zhukova 1 , Ivan Tolmachov 1 , Elena Ermak 2 & Sergey Babenko 3
1Siberian State Medical University, Tomsk, Russian Federation; 2Medical Institute named S.Berezin, Tomsk, Russian Federation; 3Edical Institute named S.Berezin, Tomsk, Russian Federation.
The goal was to study neuroplasticity in patients with diabetes mellitus using neuroimaging techniques. We examined 80 patients with diabetes mellitus type 1 and 2. All were conducted general clinical examination, neuropsychological testing - MoCa test, test 12 words. All patients underwent continuous glycemic monitoring and HbA1c assessment. An MRI study was also performed on Siemens 1.5 T, the protocol included a standard examination of the brain, a proton spectroscopy, and functional MRI at rest and with paradigms. As a result, changes in the metabolites in the hippocampus were found in patients with diabetes mellitus type 1 and in the temporal and frontal areas in patients with type 2 diabetes mellitus. Resting fMRI revealed many artifacts, however, quiescent networks were identified. When conducting the exercise with a load, zones of activation were identified for various stimuli, often a decrease in demand for a task.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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