Endocrine Abstracts

Diabetic patients have higher risk of urinary tract infection (UTI). Increasing of infections in patients with diabetes mellitus is conditioned by an immunosuppressive condition resulting from immune damage.

Objective: To give some dates about urinary infection in patients with diabetes mellitus, that are presented for consultation at the service of Endocrinology in the American Hospital, Tirana, Albania

Material: This study was conducted on urine samples from 125 adults diabetic patients that’s were presented for evaluation at the American Hospital, Tirana, Albania. In order to quantify the uropathogens, midstream urine samples were collected in sterile leak proof culture bottles and streaked onto diverse bacteriological media. The antimicrobial susceptibility test was performed to determine the resistance/susceptibility pattern of isolated uropathogens.

Results: Mean age resulted 58.7 years old and S.D.±21.7. Females were 66.4%. Asymptomatic patients were 26.4% of patients. Based on their medical anamnesis 42.4% of patiens were classified as patient with chronic UTI. Uroculture resulted positive in 58.4%. All patients were with diabetes more than one year. Average HbA1c resulted 8.1%. The predominant isolates were Escherichia coli with 46.5%, Enterococcus faecalis 15%, Staphylococcus aureus 13.7%, Klebsiella pneumoniae 12.3%, Pseudomonas species 8.2%, Proteus mirabilis 2.7% and Citrobacter spp 1.3%. Multi-drug-resistance was observed in 12.3% of all pathogen isolations.

Conclusions: One more time this study revealed that the predominant pathogens of UTI were Gram-negative bacilli, particularly E. coli. Other uropathogens such as S. aureus and Kliebsiella spp. were the second and the third dominant pathogens isolated respectively.