Endocrine Abstracts

Introduction: Acute pancreatitis is a common disease of simple evolution in 80% of cases, but burdened with increased morbidity and mortality especially in the diabetic patient because of his atypical symptomatology delaying his diagnosis. The objective of this study is to evaluate the clinical features of acute pancreatitis in diabetic patients.

Methods: Retrospective descriptive study including 60 patients followed in the endocrinology department of Casablanca Ibn Rochd Hospital for acute pancreatic between 2016 and 2018. Acute pancreatitis is characterized by a pain syndrome associated with elevation of lipase at 3 times normal. The variables studied were clinical-biological characteristics (toxic habits, clinical signs, anthropometric measurements, biological assessment, pancreatic CT).we based on the Balthazar CT classification. Statistical analyzes were performed by SPSS 25.

Results: The average age of our patients was 42 years with a female predominance (57%), of which 12 patients had a history of chronic alcoholism. 38 patients were type 2 diabetic and 10 type 1 diabetic patients. Acute pancreatitis revealed diabetes in 44% of cases. It was stage A in 22 cases, stage B in 8 cases, stage C in 24 cases, and stage E in 6 cases. Etiologies of acute pancreatitis were hypertriglyceridemia in 17 cases, lithiasis in 39 cases, hypercalcemia in one case, autoimmune origin in one case and idiopathic in 2 cases. Clinical signs of acute pancreatitis were dominated by mild abdominal pain of gravitational epigastric site in 45% of patients with food-induced vomiting in 35% of cases, 28% by ketotic decompensation. Evolution was marked by the regression of the symptomatology in 80% of the cases and a death by the infectious complications in 4 cases.