Endocrine Abstracts

Introduction: The diabetic patient in times of imbalance is susceptible to infections with a risk five times higher than non-diabetics. The aim of our work was to determine the clinical and paraclinical manifestations of soft-tissue infections in diabetic patients, to identify contributing factors and etiologies.

Patients and methods: Prospective study, conducted from October 2017 to September 2018, in the endocrinology department of Ibn Rochd University Hospital, in patients with soft-tissue infections outside the diabetic foot.

Results: Our series included 120 patients, mean age 40±13.8 years with a sex ratio H/F of 0.76, an average BMI of 24.9±3.9 kg/m², diabetes mellitus Type 2 predominant 62.5%, average seniority 7.2±4.45 years, average HBA1c 10.14±2.4%. The various infections found were: a simple dermohypodermitis 34.2%, complicated 8.3%, a folliculitis 4.2%, gangrene supply 9.2%, nasolabial cellulitis 10.8%, abdominal 5.8%, diaper abscess 10%, injection site 5%, back 8.3% and anthrax 4.2%. The front door was trauma (38%), intertrigo inter-toe (28.6%). Infections were related to neuropathy (P=0.02). Clinical signs were fever (36%), infected site pain (60%) and asymptomatic 4%. The results achieved found a high CRP (65%), hyperleukocytosis (60%), abscesses unique to ultrasound (32.4%). Staphylococcus aureus and streptococcus were the main isolated organisms. Treatment consisted of intensified insulin therapy, antibiotic injectable monotherapy (60%), dual therapy (30%) and triple therapy (10%). Surgical drainage achieved in 40%. The evolution was favorable in 95% and 5% of patients lost to follow-up.

Conclusion: Our study highlights the high prevalence of infections in young people due to poor hygiene, the feature is sometimes the absence of germ found. The most often favorable evolution, the means of prevention by an education, the glycemic balance are necessary.