Endocrine Abstracts

Objectives: 1. To evaluate the effect after two years of bariatric surgery on comorbidities in patients with diabetes mellitus type 2 (DMT2) and obesity grade II or higher.

2. Analyze the surgical complications in these patients.

Material and methods: Cohort study with intrasubject measures (before-after) in patients with grade II or higher obesity and T2DM, who underwent bariatric surgery (gastric bypass or vertical gastrectomy) at the Puerta del Mar Hospital in Cádiz during the period from 2005 to 2015. We analyzed anthropometric parameters, cardiovascular risk factors and complications related to surgery at baseline and 2 years after the intervention.

Results: Of the 333 patients who underwent bariatric surgery in that period, 87 had T2DM prior to surgery. 63.2% (n=55) women, with a mean age of 44.20±10.24 years and a BMI prior to surgery of 50.72±7.81 Kg/m² and 32.67±6.12 Kg/m² after surgery. The percentage of overweight lost was 63.51±18.61%. 54% (n=47) were operated on by gastric bypass and 46% (n=40) by vertical gastrectomy. The resolution rate of diabetes was 77.6% (n=66). In most cases, the duration of diabetes was less than 10 years and there were no known chronic complications. The average HbA1c prior to surgery was 7.48±1.52% and 5.66±0.98% at two years. 29.1% (n=25) are smokers, 71.3% (n=62) have high blood pressure and 69% (n=60) have dyslipidemia. The resolution of these comorbidities occurred in 61.7% and 71.7% of the cases respectively (P<0.001). 12% (n=10) of the patients presented early surgical complications and 14.8% (n=12) developed late complications.

Conclusions: In patients with obesity grade II or higher and T2DM, bariatric surgery is shown in our environment as an effective tool in the early resolution of diabetes, in addition to its beneficial effects on the rest of associated metabolic comorbidities and with a rate of surgical complications similar to other series.