Endocrine Abstracts

Recent guidelines on diabetes treatment provide that bariatric surgery should be the most logical & cost-effective means of controlling Type 2 diabetes.

Objectives: To compare laparoscopic mini-gastric bypass vs laparoscopic sleeve gastrectomy regarding the efficacy of control of D.M in obese patients.

Summary: A randomized controlled study conducted on 60 obese patients with type 2 D.M divided into, group (1): 30 patients treated by laparoscopic Sleeve gastrectomy (SG), group 2: 30 patients treated by laparoscopic Mini-Gastric Bypass (MGB). They were Type 2 Diabetic patients, above 18 years, (BMI) ≥30 kg/m², willing to sign an informed consent & comply with the follow up schedule. All patients were subjected to History taking, physical examination, laboratory & imaging investigation. The study was approved by the ethical committee of the faculty of medicine.

Key messages: The MGB group had greater FBG reduction (37.80±6.41 mg/dl) vs (29.93±12.84 mg/dl) in SG group and this was statistically significant (P value <0.004). The mean HBA1c drop after one year in MGB (2.33±0.48%) vs (2.01±0.59%) in SG group which was statistically significant (P<0.024). In the MGB group, diabetes resolution at 6 months was 46.7% vs 20% in the SG.

Conclusion: MGB has better& earlier effect than SG in diabetes remission. OHG, C peptide >3 ng/ml and diabetes duration <5 years are considered independent significant predictors for diabetes resolution.