Endocrine Abstracts

Background: İt is known that there is a relationship between some diseases and blood groups.

Objective: The objective of our study is to investigate how often ABO and Rh blood groups are seen in benign thyroid diseases, especially in autoimmune-mediated thyroid diseases, and hence whether there is an association between blood groups and thyroid diseases.

Method: A total of 958 patients who were followed due to any benign thyroid disease were included in the study.

Results: The study population comprised 958 patients, 550 with Hashimoto’s hypothyroidism, 160 with non-Hashimoto’s hypothyroidism, 103 with iatrogenic hypothyroidism, 93 with secondary hypothyroidism, and 28 with Graves’ and 24 with non-Graves’ hyperthyroidism. Of the patients, 47.1% belonged to the O blood group, 30% to the A blood group, 15.2% to the B blood group, and 7.7% to the AB blood group while 90% were Rh-positive. The ratio of those with the O blood group was determined to be significantly higher in the Hashimoto’s hypothyroidism group compared to the other disease groups. In the non-Hashimoto’s hypothyroidism group, however, the ratio of the AB blood group was statistically significantly higher. While autoimmune diseases were more common in those with the O blood group, they were significantly lower in the AB blood group (P<0.001).

Conclusion: In our study, we determined that the ratio of the O blood group was significantly higher among patients with hypothyroidism due to Hashimoto’s thyroiditis. This suggests that the O blood group might be a risk factor for Hashimoto’s disease.